What are they?
Exosomes are microscopic, cell-derived particles that play a key role in communication between skin cells. They’re part of a broader system called cell-to-cell signalling, where they help coordinate repair, regeneration, and immune responses in the skin. In the context of advanced skincare and aesthetics, exosomes are gaining traction for their ability to support healing and improve skin texture, tone, and resilience.
Naturally released by cells such as fibroblasts, stem cells, and platelets, exosomes carry molecular cargo including proteins, lipids, and RNA. These components help regulate biological processes like collagen synthesis, inflammation control, and skin barrier repair. When used in skincare or clinical treatments, exosomes effectively deliver these signals to other skin cells, encouraging them to behave in a healthier, more youthful way.
How are they used?
In clinical aesthetics, exosome-rich formulas are commonly applied after procedures like microneedling, laser treatments, or radiofrequency. These treatments create controlled micro-injuries to stimulate the skin’s natural renewal process. Applying exosomes immediately afterwards may help accelerate recovery, reduce post-procedure inflammation, and enhance collagen production for longer-term results.
Exosomes are not living cells, so they bypass many of the regulatory complexities associated with stem cell therapies. However, their effectiveness depends heavily on how they’re sourced, purified, and stabilised. Most commercially used exosomes are derived from mesenchymal stem cells or platelets, though ongoing research is exploring other sources and delivery methods.
Exosomes in skincare
In skincare, exosomes are now appearing in serums and ampoules aimed at barrier repair, calming sensitivity, and boosting hydration. Although their penetration is limited in topical form, their ability to support the skin’s own repair pathways makes them a promising addition to targeted routines.
They are currently being studied for their potential benefits in managing pigmentation, acne scarring, inflammation, and general signs of ageing. That said, exosomes are not a universal solution. They work best as part of a broader treatment plan, especially in clinic settings where skin is primed to respond.
