---
title: Squalane and Squalene
description: "### What is it? Squalane and squalene are both derived from squalene, a lipid naturally produced by our skin. Squalene, in its natural state, is unstable and prone to oxidation. To make it suitable for skincare, it is hydrogenated into…"
url: "https://www.dralexisgranite.com/glossary/squalane-and-squalene/"
updated: "2025-12-08"
category: General
---

# Squalane and Squalene

### What is it?

Squalane and squalene are both derived from squalene, a lipid naturally produced by our skin. Squalene, in its natural state, is unstable and prone to oxidation. To make it suitable for skincare, it is hydrogenated into squalane, a more stable and effective form

### How does it work?

In dermatology, squalane is widely used in moisturisers, serums, and oils for its hydrating and skin-softening properties. It mimics the skin’s natural [sebum](https://www.dralexisgranite.com/glossary/sebum/), making it an excellent emollient for all skin types.

The benefits of squalane include lightweight hydration, improved skin elasticity, and reduced dryness. It’s [non-comedogenic](https://www.dralexisgranite.com/glossary/non-comedogenic/), meaning it won’t clog pores, and it works well for sensitive skin. Squalane provides a simple, effective way to replenish the skin’s natural moisture barrier.